WOMEN'S HEALTH
Progesterone
with clinical guidance.
Understand progesterone and its role in an individual menopause hormone therapy plan.
Understand your treatment options.
Progesterone may be prescribed alongside systemic estrogen for people with a uterus to help protect the uterine lining. The need for it, the formulation and the schedule depend on your clinical assessment.
Estradiol and progesterone are not interchangeable. Your clinician determines whether one or both belong in your treatment plan and explains follow-up.
What to discuss before treatment.
Discuss your medical history, other medicines, unexplained vaginal bleeding, cancer history, blood clots, liver disease and allergies before treatment. Review the exact product labeling for its risks, side effects and contraindications.
This overview does not include every risk, contraindication or interaction. Read the full information for the exact product and discuss questions with your clinician.
Your care starts with a conversation.
Review your health history, current medicines and treatment goals with a clinician. Treatment and prescriptions depend on clinical suitability and availability. Confirm the exact product, formulation, total cost and follow-up arrangements before proceeding.
Online patient intake is coming soon. These pages introduce the planned care options; they do not provide an active checkout or guarantee a prescription.
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Frequently asked questions
Why is progesterone sometimes prescribed with estrogen?
When systemic estrogen is used by a person with a uterus, a progestogen such as progesterone helps protect the uterine lining. The exact plan depends on clinical assessment.
Are progesterone and estradiol interchangeable?
No. They have different roles in hormone therapy. Your clinician decides whether either or both are appropriate and explains the product-specific schedule.
How often should a hormone therapy plan be reviewed?
ACOG recommends discussing continued hormone therapy with your clinician every year. Changes in symptoms, benefits and risks may affect the decision.
Sources: ACOG hormone therapy information